BDBM335538 6-(N-tert- butylsulfamoylmethoxy)- 1-(2-((2S,4R)-2-(2'-chloro- 2-fluorobiphenyl-3- ylcarbamoyl)-4- fluoropyrrolidin-1-yl)-2- oxoethyl)-1H-indazole-3- carboxamide::US10550140, Compound 28::US9732104, Compound 28

SMILES CC(C)(C)NS(=O)(=O)COc1ccc2c(nn(CC(=O)N3C[C@H](F)C[C@H]3C(=O)Nc3cccc(c3F)-c3ccccc3Cl)c2c1)C(N)=O

InChI Key InChIKey=QKHSAOKIKYLPSQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 335538   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM335538(US9732104, Compound 28 | 6-(N-tert- butylsulfamoyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM335538(US9732104, Compound 28 | 6-(N-tert- butylsulfamoyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2019
Entry Details
US Patent