BDBM336120 US9738658, Example 2

SMILES Nc1ncnc2OCCN(c3cnc4n(ccc4c3)-c3cccc(OC(F)(F)F)c3)C(=O)c12

InChI Key InChIKey=ZRKOYFKSQCPPNH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336120   

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM336120(US9738658, Example 2)
Affinity DataIC50:  0.5nMAssay Description:For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent