BDBM336317 5-(1-acetyl-7- chloroindolin-5-yl) 4- methylnicotinotrile::US9745282, 10

SMILES CC(=O)N1CCc2cc(cc(Cl)c12)-c1cncc(C#N)c1C

InChI Key InChIKey=NWUSEUUSCCJWDR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336317   

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336317(5-(1-acetyl-7- chloroindolin-5-yl) 4- methylnicoti...)
Affinity DataIC50:  300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336317(5-(1-acetyl-7- chloroindolin-5-yl) 4- methylnicoti...)
Affinity DataIC50:  35nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent