BDBM336540 1-(7-chloro-5-(5- fluoropyridin-3- yl)indon-1-yl)- 2,2,2- trifluoroethanone::US9745282, 32

SMILES Fc1cncc(c1)-c1cc2CCN(C(=O)C(F)(F)F)c2c(Cl)c1

InChI Key InChIKey=GQLSZAQYIVRDJO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336540   

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336540(1-(7-chloro-5-(5- fluoropyridin-3- yl)indon-1-yl)-...)
Affinity DataIC50:  525nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336540(1-(7-chloro-5-(5- fluoropyridin-3- yl)indon-1-yl)-...)
Affinity DataIC50:  10.6nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent