BDBM337278 (4-{2-[2-(3,5-dimethoxyphenyl)ethyl]-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenyl)methanol::US9745311, Example 13

SMILES COc1cc(CCc2cnc3[nH]c(cc3n2)-c2ccc(CO)cc2)cc(OC)c1

InChI Key InChIKey=SQZYQOSLZUDVFN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 337278   

TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM337278((4-{2-[2-(3,5-dimethoxyphenyl)ethyl]-5H-pyrrolo[2,...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to detect product fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM337278((4-{2-[2-(3,5-dimethoxyphenyl)ethyl]-5H-pyrrolo[2,...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to detect product fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM337278((4-{2-[2-(3,5-dimethoxyphenyl)ethyl]-5H-pyrrolo[2,...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to detect product fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent