BDBM337802 Ethyl 2,4-dioxo-1-[4-(2-oxo-1,3-oxazolidin-3-yl)phenyl]-3-[5-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalen-1-yl]-1,2,3,4-tetrahydropyrimidine-5-carboxylate (racemate)::US9751843, 196

SMILES CCOC(=O)c1cn(-c2ccc(cc2)N2CCOC2=O)c(=O)n(C2CCCc3c2cccc3C(F)(F)F)c1=O

InChI Key InChIKey=VSDGHEFQEONBCP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337802   

TargetChymase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM337802(Ethyl 2,4-dioxo-1-[4-(2-oxo-1,3-oxazolidin-3-yl)ph...)
Affinity DataIC50:  22nMAssay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent