BDBM339792 US10202340, Example 11

SMILES O[C@@H]([C@@H](CN1CCCC1)NC(=O)CC1Cc2ccccc2C1)c1ccc(OCC2CC2)cc1

InChI Key InChIKey=SVAHPDAGMJVRLL-IXCJQBJRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 339792   

TargetCeramide glucosyltransferase(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM339792(US10202340, Example 11)
Affinity DataIC50:  46nMAssay Description:Inhibition of GlcCer synthesis in broken wild-type MDCK cell preparationsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCeramide glucosyltransferase(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM339792(US10202340, Example 11)
Affinity DataIC50:  0.840nMAssay Description:)Inhibition of GlcCer production in MDCKII cells stably expressing human MDR1 (obtained from The Netherlands Cancer Institute).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCeramide glucosyltransferase(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM339792(US10202340, Example 11)
Affinity DataIC50:  1nMAssay Description:Inhibition of GlcCer production in whole wild-type MDCKII cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent