BDBM339966 5,6-difluoro-3-(pyridin-3-yl)- 1H-indole::US9758505, 47

SMILES Fc1cc2[nH]cc(-c3cccnc3)c2cc1F

InChI Key InChIKey=IXKGPYFXBWMXPZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 339966   

TargetTryptophan 2,3-dioxygenase(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM339966(US9758505, 47 | 5,6-difluoro-3-(pyridin-3-yl)- 1H-...)
Affinity DataIC50: 2.80E+3nMAssay Description:The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent