BDBM339968 3-(6-fluoro-1H-indol-3- yl)pyridine 1-oxide::US9758505, 49

SMILES [O-][n+]1cccc(c1)-c1c[nH]c2cc(F)ccc12

InChI Key InChIKey=UYWRKNOWRAPAJQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 339968   

TargetTryptophan 2,3-dioxygenase(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM339968(US9758505, 49 | 3-(6-fluoro-1H-indol-3- yl)pyridin...)
Affinity DataIC50: 1.10E+4nMAssay Description:The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent