BDBM340781 (E)-1-(5-(But-2-en-1-yl)-4-propoxy-2′-(1H-tetrazol-5-yl)-[1,1′-biphenyl]-3-yl)-3-(p-tolyl)urea::US9765018, Example 19

SMILES CCCOc1c(C\C=C\C)cc(cc1NC(=O)Nc1ccc(C)cc1)-c1ccccc1-c1nnn[nH]1

InChI Key InChIKey=XLJFBPWYRXLPJP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340781   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM340781(US9765018, Example 19 | (E)-1-(5-(But-2-en-1-yl)-4...)
Affinity DataIC50: 30nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2019
Entry Details
US Patent