BDBM341273 (R)-5-chloro-2-(4-(2,6-diamino-5-chloropyrimidin-4-yl)morpholin-3-yl)-3-phenylquinazolin-4(3H)-one ::US9765060, Compound 100

SMILES Nc1nc(N)c(Cl)c(n1)N1CCOC[C@H]1c1nc2cccc(Cl)c2c(=O)n1-c1ccccc1

InChI Key InChIKey=VBFRFRVPVIHNJU-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341273   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Gilead Sciences

US Patent

LigandBDBM341273(US9765060, Compound 100 | (R)-5-chloro-2-(4-(2,6-d...)Copy SMILESCopy InChI

Affinity DataIC50: 8.40E+3nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
7/29/2019
Entry Details
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