BDBM341618 2-(2-chloro-4-(morpholinomethyl)phenoxy)-1-(5-(3,4-dimethoxyphenyl)-7,8-dihydrothiazolo[2',3':2,3]-imidazo[4,5-c]pyridin-6(5H)-yl)ethanone::US9765092, Example 6.1.2

SMILES COc1ccc(cc1OC)C1N(CCc2nc3sccn3c12)C(=O)COc1ccc(CN2CCOCC2)cc1Cl

InChI Key InChIKey=RNMMDYOWHRACKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341618   

TargetTryptophan 5-hydroxylase 1(Human)
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM341618(US9765092, Example 6.1.2 | 2-(2-chloro-4-(morpholi...)
Affinity DataIC50: 5nMAssay Description:To generate the enzyme, full length human TPH1 is cloned into the plasmid pET20b(+) (Novagen) and expressed in E. coli. The bacterial cells are ruptu...More data for this Ligand-Target Pair
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Date in BDB:
7/29/2019
Entry Details
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