BDBM342515 3-Methyl-1-phenyl-6-(4-piperazin-1-yl-phenyl)-1H-pyrazolo[3,4-b]pyridin-4-ol::US9771375, Example 97

SMILES CCc1nn(-c2ccccc2)c2nc(nc(O)c12)-c1ccc(cc1)N1CCNCC1

InChI Key InChIKey=JWTZIQRHGOGTEB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342515   

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 342515BDBM342515(US9771375, Example 97 | 3-Methyl-1-phenyl-6-(4-pip...)
Affinity DataIC50: 2.71E+3nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent