BDBM342530 US10329299, Compound 81::US10675286, Compound 81::US11541059, Compound 81::US9775844, Compound 81

SMILES C[C@H](NC(=O)c1c(N)nn2cccnc12)c1cc2cccc(C#Cc3cn(C)cn3)c2c(=O)n1-c1ccccc1

InChI Key InChIKey=CNBSUEZPDYCMKK-UHFFFAOYSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 342530   

LigandPNGBDBM342530(US9775844, Compound 81 | US10329299, Compound 81 |...)
Affinity DataIC50: 2.00E+3nMAssay Description:PI3 Kinase α, β, γ or δ activity was assayed using the PI3 Kinase HTRF assay kit (catalogue No. 33-016) purchased from Millipore ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

LigandPNGBDBM342530(US9775844, Compound 81 | US10329299, Compound 81 |...)
Affinity DataIC50: 2.00E+3nMAssay Description:PI3 Kinase α, β, γ or δ activity was assayed using the PI3 Kinase HTRF assay kit (catalogue No. 33-016) purchased from Millipore ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

LigandPNGBDBM342530(US9775844, Compound 81 | US10329299, Compound 81 |...)
Affinity DataIC50: 2.00E+3nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
US Patent

LigandPNGBDBM342530(US9775844, Compound 81 | US10329299, Compound 81 |...)
Affinity DataIC50: 2.00E+3nMAssay Description:PI3 Kinase α, β, γ or δ activity was assayed using the PI3 Kinase HTRF assay kit (catalogue No. 33-016) purchased from Millipore ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

LigandPNGBDBM342530(US9775844, Compound 81 | US10329299, Compound 81 |...)
Affinity DataIC50: 2.00E+3nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
US Patent

LigandPNGBDBM342530(US9775844, Compound 81 | US10329299, Compound 81 |...)
Affinity DataIC50: 2.00E+3nMAssay Description:A PI3-Kinase HTRF assay kit (cat No. 33-016) purchased from Millipore Corporation was used to screen compounds provided herein. This assay used speci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

LigandPNGBDBM342530(US9775844, Compound 81 | US10329299, Compound 81 |...)
Affinity DataIC50: 2.00E+3nMAssay Description:A PI3-Kinase HTRF assay kit (cat No. 33-016) purchased from Millipore Corporation was used to screen compounds provided herein. This assay used speci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

LigandPNGBDBM342530(US9775844, Compound 81 | US10329299, Compound 81 |...)
Affinity DataIC50: 2.00E+3nMAssay Description:A PI3-Kinase HTRF assay kit (cat No. 33-016) purchased from Millipore Corporation was used to screen compounds provided herein. This assay used speci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

LigandPNGBDBM342530(US9775844, Compound 81 | US10329299, Compound 81 |...)
Affinity DataIC50: 2.00E+3nMAssay Description:A PI3-Kinase HTRF assay kit (cat No. 33-016) purchased from Millipore Corporation was used to screen compounds provided herein. This assay used speci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2021
Entry Details
US Patent

LigandPNGBDBM342530(US9775844, Compound 81 | US10329299, Compound 81 |...)
Affinity DataIC50: 2.00E+3nMAssay Description:A PI3-Kinase HTRF assay kit (cat No. 33-016) purchased from Millipore Corporation was used to screen compounds provided herein. This assay used speci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2021
Entry Details
US Patent

LigandPNGBDBM342530(US9775844, Compound 81 | US10329299, Compound 81 |...)
Affinity DataIC50: 2.00E+3nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
US Patent

LigandPNGBDBM342530(US9775844, Compound 81 | US10329299, Compound 81 |...)
Affinity DataIC50: 2.00E+3nMAssay Description:A PI3-Kinase HTRF assay kit (cat No. 33-016) purchased from Millipore Corporation was used to screen compounds provided herein. This assay used speci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2021
Entry Details
US Patent

LigandPNGBDBM342530(US9775844, Compound 81 | US10329299, Compound 81 |...)
Affinity DataIC50: 3.00E+3nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
US Patent

LigandPNGBDBM342530(US9775844, Compound 81 | US10329299, Compound 81 |...)
Affinity DataIC50: 3.00E+3nMAssay Description:PI3 Kinase α, β, γ or δ activity was assayed using the PI3 Kinase HTRF assay kit (catalogue No. 33-016) purchased from Millipore ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

LigandPNGBDBM342530(US9775844, Compound 81 | US10329299, Compound 81 |...)
Affinity DataIC50: 3.00E+3nMAssay Description:A PI3-Kinase HTRF assay kit (cat No. 33-016) purchased from Millipore Corporation was used to screen compounds provided herein. This assay used speci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2021
Entry Details
US Patent

LigandPNGBDBM342530(US9775844, Compound 81 | US10329299, Compound 81 |...)
Affinity DataIC50: 3.00E+3nMAssay Description:A PI3-Kinase HTRF assay kit (cat No. 33-016) purchased from Millipore Corporation was used to screen compounds provided herein. This assay used speci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent