BDBM342657 5-(4-Cyclobutyl-piperazin-1-ylmethyl)-thiophene-2-carboxylic acid 2,4-dichloro-benzylamide::US9776991, Example 27

SMILES Clc1ccc(CNC(=O)c2ccc(CN3CCN(CC3)C3CCC3)s2)c(Cl)c1

InChI Key InChIKey=ZLKQYGJIGGGJKS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342657   

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandPNGBDBM342657(5-(4-Cyclobutyl-piperazin-1-ylmethyl)-thiophene-2-...)
Affinity DataIC50:  0.803nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent