BDBM342664 5-[4-(2,4-Dimethyl-6-oxo-6H-pyran-3-carbonyl)-piperazin-1-ylmethyl]-thiophene-2-carboxylic acid (2-methoxy-pyridin-4-ylmethyl)-amide::US9776991, Example 34

SMILES COc1cc(CNC(=O)c2ccc(CN3CCN(CC3)C(=O)c3c(C)cc(=O)oc3C)s2)ccn1

InChI Key InChIKey=DYAUFULBAGMSRN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342664   

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandPNGBDBM342664(5-[4-(2,4-Dimethyl-6-oxo-6H-pyran-3-carbonyl)-pipe...)
Affinity DataIC50:  0.906nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent