BDBM343280 4-(4-(difluoromethyl)thiazol-2-yl)-1-methyl-N-(2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1H-pyrazole-5-carboxamide::US9777000, Example 3.15

SMILES Cn1ncc(-c2nc(cs2)C(F)F)c1C(=O)Nc1ccn2nc(nc2c1)-c1ccccc1

InChI Key InChIKey=DAYYTMBBMJXEKP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 343280   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Mochida Pharmaceutical

US Patent
LigandPNGBDBM343280(4-(4-(difluoromethyl)thiazol-2-yl)-1-methyl-N-(2-p...)
Affinity DataIC50: 5nMAssay Description:IMAP TR-FRET Phosphodiersterase Evaluation Assay Kit (Molecular Device) was used for the measurement. Ten μL of a diluted test compound having e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent