BDBM345274 2-[[5-(4-Chlorophenyl)-1-[(2- chlorophenyl)methyl]pyrazol-3- yl]methoxy]-2-methyl-propanamide 1H NMR (CD3OD 400 MHz) $#948; 1.46 (s, 6H), 4.58 (s, 2H), 5.40 (s, 2H), 6.52 (s, 1H), 6.71-6.76 (m, 1H), 7.20-7.58 (m, 6H)::US10202350, Example 20::US11292767, Example 20::US11724989, Example 20

SMILES CC(C)(OCc1cc(-c2ccc(Cl)cc2)n(Cc2ccccc2Cl)n1)C(N)=O

InChI Key InChIKey=IBNAYOBYCPXGCL-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 345274   

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandPNGBDBM345274(2-[[5-(4-Chlorophenyl)-1-[(2- chlorophenyl)methyl...)
Affinity DataIC50:  1.70E+4nMAssay Description:MCT4 may be stably expressed in MDA-MB-453 breast cancer cells that do not express native MCT1 or MCT4. MCT4 activity may be assessed by monitoring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandPNGBDBM345274(2-[[5-(4-Chlorophenyl)-1-[(2- chlorophenyl)methyl...)
Affinity DataIC50:  2.20E+4nMAssay Description:NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMalignant T-cell-amplified sequence 1(Human)
Vettore

US Patent
LigandPNGBDBM345274(2-[[5-(4-Chlorophenyl)-1-[(2- chlorophenyl)methyl...)
Affinity DataIC50:  454nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMonocarboxylate transporter 1(Human)
Vettore

US Patent
LigandPNGBDBM345274(2-[[5-(4-Chlorophenyl)-1-[(2- chlorophenyl)methyl...)
Affinity DataIC50:  7.90E+3nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMonocarboxylate transporter 1(Human)
Vettore

US Patent
LigandPNGBDBM345274(2-[[5-(4-Chlorophenyl)-1-[(2- chlorophenyl)methyl...)
Affinity DataIC50:  7.90E+3nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandPNGBDBM345274(2-[[5-(4-Chlorophenyl)-1-[(2- chlorophenyl)methyl...)
Affinity DataIC50:  1.70E+4nMAssay Description:MCT4 may be stably expressed in MDA-MB-453 breast cancer cells that do not express native MCT1 or MCT4. MCT4 activity may be assessed by monitoring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandPNGBDBM345274(2-[[5-(4-Chlorophenyl)-1-[(2- chlorophenyl)methyl...)
Affinity DataIC50:  2.20E+4nMAssay Description:NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandPNGBDBM345274(2-[[5-(4-Chlorophenyl)-1-[(2- chlorophenyl)methyl...)
Affinity DataIC50:  2.20E+4nMAssay Description:NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent