BDBM345580 Propane-2-sulfonic acid [6-(1- methyl-6-oxo-1,6-dihydro-pyridin- 3-yl)-2-(1,3,5-trimethyl-1H-pyrazol- 4-yloxy)-pyrimidin-4-yl]-amide::US10202360, Example 125

SMILES CC(C)S(=O)(=O)Nc1cc(nc(Oc2c(C)nn(C)c2C)n1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=OCEGJKYOSMSHNC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345580   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM345580(Propane-2-sulfonic acid [6-(1- methyl-6-oxo-1,6-di...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent