BDBM345968 N-(2-tert-Butylamino-ethyl)-2-(4-cyclopropylmethyl-1-methyl-5-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-9-ylamino)-N-(2-trifluoromethyl-benzyl)-acetamide::US10202368, Example 43

SMILES CN1CCN(CC2CC2)C(=O)c2cccc(NCC(=O)N(CCNC(C)(C)C)Cc3ccccc3C(F)(F)F)c12

InChI Key InChIKey=DNUCGAXXCQAXPI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345968   

TargetAtypical chemokine receptor 3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM345968(US10202368, Example 43 | N-(2-tert-Butylamino-ethy...)
Affinity DataEC50:  4nMAssay Description:The assay is using the PathHunter CHO-K1 CXCR7 β-arrestin cell line from DiscoverX. The system is based on the Enzyme Fragment Complementation T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent