BDBM346268 2-[4-(2-methylpyrazol-3-yl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridyl)acetamide::US10202375, Example 31

SMILES Cn1nccc1-c1ccnc2n(CC(=O)Nc3ccc(cn3)-c3cnccn3)ccc12

InChI Key InChIKey=PBKYMUKGCGCPRU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346268   

TargetProtein Wnt-3a(Mus musculus)
Redx Pharma

US Patent
LigandPNGBDBM346268(2-[4-(2-methylpyrazol-3-yl)pyrrolo[2,3-b]pyridin-1...)
Affinity DataIC50:  0.890nMAssay Description:Mouse L cells transfected to constitutively produce biologically active murine Wnt-3a, referred to as L-Wnt cells, were purchased from the American T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Mus musculus)
Redx Pharma

US Patent
LigandPNGBDBM346268(2-[4-(2-methylpyrazol-3-yl)pyrrolo[2,3-b]pyridin-1...)
Affinity DataIC50: <1nMAssay Description:Mouse L cells transfected to constitutively produce biologically active murine Wnt-3a, referred to as L-Wnt cells, were purchased from the American T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent