BDBM346488 4-(3-cyclopropyl-3-hydroxy-but-1-ynyl)-2,6-dimethyl-3-(5-tetrahydrofuran-3-yl-1,3,4-oxadiazol-2-yl)-1H-pyrrolo[2,3-c]pyridin-7-one::US10202378, Example 175::US10202378, Example 96a::US10202378, Example 96b
SMILES Cc1[nH]c2c(c1-c1nnc(o1)C1CCOC1)c(cn(C)c2=O)C#CC(C)(O)C1CC1
InChI Key
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 346488
Affinity DataIC50: 46.7nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Affinity DataIC50: 248nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Affinity DataIC50: 1.14E+3nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Affinity DataIC50: 182nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Affinity DataIC50: 40.7nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair