BDBM346490 4-(3-cyclopropyl-3-hydroxy-but-1-ynyl)-3-[5-[(dimethylamino)methyl]-1,3,4-oxadiazol-2-yl]-2,6-dimethyl-1H-pyrrolo[2,3-c]pyridin-7-one::US10202378, Example 185::US10202378, Example 97a::US10202378, Example 97b
SMILES CN(C)Cc1nnc(o1)-c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)C1CC1
InChI Key
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 346490
Affinity DataIC50: 56.1nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Affinity DataIC50: 324nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Affinity DataIC50: 205nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Affinity DataIC50: 1.24E+3nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Affinity DataIC50: 30.8nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Affinity DataIC50: 385nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair