BDBM346522 US10202378, Example 126::isobutyl 4-(3-cyclopropyl-3-hydroxy-but-1-ynyl)-2,6-dimethyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-3-carboxylate

SMILES CC(C)COC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)C1CC1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346522   

LigandPNGBDBM346522(US10202378, Example 126 | isobutyl 4-(3-cyclopropy...)
Affinity DataIC50:  123nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM346522(US10202378, Example 126 | isobutyl 4-(3-cyclopropy...)
Affinity DataIC50:  40.1nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent