BDBM346562 2-cyanoethyl 2,6-dimethyl-7-oxo-4-(4,4,4-trifluoro-3-hydroxy-3-phenyl-but-1-ynyl)-1H-pyrrolo[2,3-c]pyridine-3-carboxylate::US10202378, Example 166

SMILES Cc1[nH]c2c(c1C(=O)OCCC#N)c(cn(C)c2=O)C#CC(O)(c1ccccc1)C(F)(F)F

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346562   

LigandPNGBDBM346562(2-cyanoethyl 2,6-dimethyl-7-oxo-4-(4,4,4-trifluoro...)
Affinity DataIC50:  214nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM346562(2-cyanoethyl 2,6-dimethyl-7-oxo-4-(4,4,4-trifluoro...)
Affinity DataIC50:  31.2nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent