BDBM347314 N-(3-Chloro-4-fluorophenyl)-N′-hydroxy-4-({2-[(methylsulfonyl)amino]ethyl}amino)-1,2,5-oxadiazole-3-carboximidamide::US20240173303, Example 6::US9789094, 6

SMILES CS(=O)(=O)NCCNc1nonc1\C(Nc1ccc(F)c(Cl)c1)=N\O

InChI Key InChIKey=WIHANXODBMGZHO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347314   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte Holdings

US Patent
LigandPNGBDBM347314(N-(3-Chloro-4-fluorophenyl)-N′-hydroxy-4-({2...)
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte Holdings

US Patent
LigandPNGBDBM347314(N-(3-Chloro-4-fluorophenyl)-N′-hydroxy-4-({2...)
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenase (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent