BDBM347649 2-methoxy-6-[2-[4-[1-methyl-4-(4-pyridyl)pyrazol-3-yl]phenyl]ethynyl]pyridine::US9790203, Example 20

SMILES COc1cccc(n1)C#Cc1ccc(cc1)-c1nn(C)cc1-c1ccncc1

InChI Key InChIKey=LQIHSQPZKMNNDN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347649   

LigandPNGBDBM347649(2-methoxy-6-[2-[4-[1-methyl-4-(4-pyridyl)pyrazol-3...)
Affinity DataIC50: 100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent