BDBM350213 US10208056, Compound 45

SMILES COCCn1c(cc2c1-c1ccncc1OC2(C)C)C(N)=O

InChI Key InChIKey=KVXMBXJEXMWXLQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 350213   

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM350213(US10208056, Compound 45)
Affinity DataIC50: 4.64nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetCyclin-C/Cyclin-dependent kinase 19(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM350213(US10208056, Compound 45)
Affinity DataIC50: 11.5nMAssay Description:The binding assay relies on the LanthaScreen Eu-Kinase Binding Assay (Invitrogen). This is a kinase assay platform based on measuring the binding and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase haspin(Human)
F.S.P. Cnio

US Patent
LigandPNGBDBM350213(US10208056, Compound 45)
Affinity DataIC50: 182nMAssay Description:The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent