BDBM350389 4-amino-6-((1-(3-chloro-6-phenylimidazo[1,2-b]pyridazin-7-yl)ethyl)amino)pyrimidine-5-carbonitrile::US10208066, Compound 2::US10208066, Compound 80::US10611777, Compound 2
SMILES CC(Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1ccccc1
InChI Key InChIKey=WKDBRCUUDXLTIM-UHFFFAOYSA-N
Data 15 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 350389
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hutchison Medipharma
US Patent
Hutchison Medipharma
US Patent
Affinity DataIC50: 1nMAssay Description:Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Universite de Tours
Curated by ChEMBL
Universite de Tours
Curated by ChEMBL
Affinity DataIC50: 168nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 323nMAssay Description:Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hutchison Medipharma
US Patent
Hutchison Medipharma
US Patent
Affinity DataIC50: 0.5nMAssay Description:Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Universite de Tours
Curated by ChEMBL
Universite de Tours
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...More data for this Ligand-Target Pair
Affinity DataIC50: 272nMAssay Description:Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hutchison Medipharma
US Patent
Hutchison Medipharma
US Patent
Affinity DataIC50: 1nMAssay Description:PI3K kinases including p110α/p85α and p110γ were purchased from Invitrogen, p110δ/p85α and p110β/p85α were from Mi...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Universite de Tours
Curated by ChEMBL
Universite de Tours
Curated by ChEMBL
Affinity DataIC50: 168nMAssay Description:PI3K kinases including p110α/p85α and p110γ were purchased from Invitrogen, p110δ/p85α and p110β/p85α were from Mi...More data for this Ligand-Target Pair
Affinity DataIC50: 323nMAssay Description:PI3K kinases including p110α/p85α and p110γ were purchased from Invitrogen, p110δ/p85α and p110β/p85α were from Mi...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:PI3K kinases including p110α/p85α and p110γ were purchased from Invitrogen, p110δ/p85α and p110β/p85α were from Mi...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Universite de Tours
Curated by ChEMBL
Universite de Tours
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Universite de Tours
Curated by ChEMBL
Universite de Tours
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hutchison Medipharma
US Patent
Hutchison Medipharma
US Patent
Affinity DataIC50: 87nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Universite de Tours
Curated by ChEMBL
Universite de Tours
Curated by ChEMBL
Affinity DataIC50: 168nMAssay Description:Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...More data for this Ligand-Target Pair