BDBM350477 Methyl N-[(14S)-14-[1-(3-chloro-2-fluorophenyl)-5-methyl-1H-1,2,3-triazole-4-amido]-13-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate, TFA salt::US10208068, Example 88

SMILES COC(=O)Nc1ccc-2c(NC(=O)CCCC(C)[C@H](NC(=O)c3nnn(c3C)-c3cccc(Cl)c3F)c3cc-2ccn3)c1

InChI Key InChIKey=UCDNRVZVDNQAAN-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350477   

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM350477(Methyl N-[(14S)-14-[1-(3-chloro-2-fluorophenyl)-5-...)
Affinity DataKi:  52.6nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent