BDBM350580 1-[2-(3-aminopropyl)-3- methyl-1-oxo-1,2,3,4- tetrahydroisoquinolin-7-yl]-3- [4-(methylsulfanyl)phenyl]urea::US10208071, Compound 42::US10434112, Compound 42::US10799518, Compound 42

SMILES CSc1ccc(NC(=O)Nc2ccc3CC(C)N(CCCN)C(=O)c3c2)cc1

InChI Key InChIKey=WLKMBJOIYLPQPW-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 350580   

TargetN-formyl peptide receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM350580(1-[2-(3-aminopropyl)-3- methyl-1-oxo-1,2,3,4- tetr...)
Affinity DataEC50:  15nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetFormyl peptide receptor 2(Mouse)
Monash University

Curated by ChEMBL
LigandPNGBDBM350580(1-[2-(3-aminopropyl)-3- methyl-1-oxo-1,2,3,4- tetr...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at mouse FPR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetN-formyl peptide receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM350580(1-[2-(3-aminopropyl)-3- methyl-1-oxo-1,2,3,4- tetr...)
Affinity DataEC50:  15nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetN-formyl peptide receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM350580(1-[2-(3-aminopropyl)-3- methyl-1-oxo-1,2,3,4- tetr...)
Affinity DataEC50:  1.50E+4nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent