BDBM350582 (+) (2S,3R)-3-[(4-bromophenyl) carbamoyl]spiro[bicyclo[2.2.1] heptane-7,1'-cyclopropane]-2- carboxylic acid::US10208071, Compound 44::US10434112, Compound 44::US10799518, Compound 114

SMILES OC(=O)C1C2CCC(C1C(=O)Nc1ccc(Br)cc1)C21CC1

InChI Key

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 350582   

TargetN-formyl peptide receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM350582((+) (2S,3R)-3-[(4-bromophenyl) carbamoyl]spiro[bic...)
Affinity DataEC50: <1nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetN-formyl peptide receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM350582((+) (2S,3R)-3-[(4-bromophenyl) carbamoyl]spiro[bic...)
Affinity DataEC50: <1nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetN-formyl peptide receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM350582((+) (2S,3R)-3-[(4-bromophenyl) carbamoyl]spiro[bic...)
Affinity DataEC50:  2.90nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetN-formyl peptide receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM350582((+) (2S,3R)-3-[(4-bromophenyl) carbamoyl]spiro[bic...)
Affinity DataEC50: <1.00E+3nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent