BDBM350888 3-Phenyl-2-neopentylthio-4-oxo-3,4-dihydroquinazoline::US9796687, Compound 5

SMILES CC(C)(C)CSc1nc2ccccc2c(=O)n1-c1ccccc1

InChI Key InChIKey=GMUIDKJUSNEWSL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 350888   

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350888(US9796687, Compound 5 | 3-Phenyl-2-neopentylthio-4...)
Affinity DataIC50: 100nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM350888(US9796687, Compound 5 | 3-Phenyl-2-neopentylthio-4...)
Affinity DataIC50: 100nMAssay Description:Inhibition of full length PDE7 (unknown origin) using FAM-cAMP as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed