BDBM350889 3-(2,6-Difluorophenyl)-8-methyl-2-neopentylthio-4-oxo-3,4-dihydroquinazoline ::US9796687, Compound 6

SMILES Cc1cccc2c(=O)n(-c3c(F)cccc3F)c(SCC(C)(C)C)nc12

InChI Key InChIKey=SNWVGOLHVCHJGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350889   

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 350889BDBM350889(US9796687, Compound 6 | 3-(2,6-Difluorophenyl)-8-m...)
Affinity DataIC50: 8.67E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent