BDBM350893 2-Cyclopropylmethylthio-3-(2,6-difluorophenyl)-8-methyl-4-oxo-3,4-dihydroquinazoline::US9796687, Compound 15

SMILES Cc1cccc2c(=O)n(-c3c(F)cccc3F)c(SCC3CC3)nc12

InChI Key InChIKey=VLUTWRQNEFAJQX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350893   

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandChemical structure of BindingDB Monomer ID 350893BDBM350893(US9796687, Compound 15 | 2-Cyclopropylmethylthio-3...)
Affinity DataIC50: 4.56E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent