BDBM3510 4-N-phenylquinazoline-4,6-diamine::CHEMBL89940::PD153035 Analog 9

SMILES Nc1ccc2ncnc(Nc3ccccc3)c2c1

InChI Key InChIKey=MJMYCJSNBBYTCT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3510   

TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandChemical structure of BindingDB Monomer ID 3510BDBM3510(CHEMBL89940 | 4-N-phenylquinazoline-4,6-diamine | ...)
Affinity DataIC50: 770nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandChemical structure of BindingDB Monomer ID 3510BDBM3510(CHEMBL89940 | 4-N-phenylquinazoline-4,6-diamine | ...)
Affinity DataIC50: 776nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed