BDBM351270 CHEM-US-00081::US9796702, 31

SMILES CN1C(=O)CCc2cc(ccc12)-c1n[nH]cc1CC1CCN(CC1)C(=O)c1cncn1C

InChI Key InChIKey=RATCSTAZAVMNFV-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 351270   

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM351270(US9796702, 31 | CHEM-US-00081)
Affinity DataEC50:  0.00700nMAssay Description:The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM351270(US9796702, 31 | CHEM-US-00081)
Affinity DataEC50:  1.12nMAssay Description:The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent