BDBM35175 indazole-benzimidazole, 11

SMILES CN1CCN(c2cccc3[nH]c(-c4n[nH]c5cc(-c6ccc(N)c(F)c6)ccc45)nc23)CC1

InChI Key InChIKey=QFMIUUHQPLSESZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35175   

TargetProtein kinase C zeta type(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 35175BDBM35175(indazole-benzimidazole, 11)
Affinity DataIC50: 55.5nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 35175BDBM35175(indazole-benzimidazole, 11)
Affinity DataIC50: 1.73E+3nMT: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed