BDBM351950 US10385066, Example 26::US9796729, 26

SMILES Cc1ccc(cn1)-n1ccc2cc(cc(C3CC3)c12)N1CCOc2ncnc(N)c2C1=O

InChI Key InChIKey=SMDZZBLDUNSAPD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 351950   

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM351950(US9796729, 26 | US10385066, Example 26)
Affinity DataIC50: 3.40nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM351950(US9796729, 26 | US10385066, Example 26)
Affinity DataIC50: 3.40nMAssay Description:For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent