BDBM352035 US9802907, Compound 14::US9802907, Compound 23::US9802907, Compound 35

SMILES Cc1nc([se]c1C(O)=O)-c1ccc(-c2ccccc2)c(c1)C#N

InChI Key InChIKey=DJWSKQZSUPNTPC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 352035   

TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Jiangsu Atom Bioscience and Pharmaceutical

US Patent
LigandPNGBDBM352035(US9802907, Compound 14 | US9802907, Compound 23 | ...)
Affinity DataIC50:  1.70nMAssay Description:The inhibition of the activity of xanthine oxidase (XO) is tested through a coupled enzymatic reaction of xanthine oxidase, horseradish peroxidase (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Jiangsu Atom Bioscience and Pharmaceutical

US Patent
LigandPNGBDBM352035(US9802907, Compound 14 | US9802907, Compound 23 | ...)
Affinity DataIC50:  2.63nMAssay Description:The inhibition of the activity of xanthine oxidase (XO) is tested through a coupled enzymatic reaction of xanthine oxidase, horseradish peroxidase (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Jiangsu Atom Bioscience and Pharmaceutical

US Patent
LigandPNGBDBM352035(US9802907, Compound 14 | US9802907, Compound 23 | ...)
Affinity DataIC50:  2.37nMAssay Description:The inhibition of the activity of xanthine oxidase (XO) is tested through a coupled enzymatic reaction of xanthine oxidase, horseradish peroxidase (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent