BDBM352187 US9802920, Compound I-11::[5-Amino-1-(4-isopropoxy- phenyl)-1H-pyrazol-4-yl]- (1H-indol-2-yl)-methanone

SMILES CC(C)Oc1ccc(cc1)-n1ncc(C(=O)c2cc3ccccc3[nH]2)c1N

InChI Key InChIKey=IBNRRDRUBLNSIB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352187   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352187([5-Amino-1-(4-isopropoxy- phenyl)-1H-pyrazol-4-yl]...)
Affinity DataIC50: 7.39E+4nMAssay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of Btk, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent