BDBM352194 US9802920, Compound I-18::{5-Amino-1-[4-(2,3-difluoro- phenoxy)-2-methyl-phenyl]- 1H-pyrazol-4-yl}-(1H- benzoimidazol-2-yl)- methanone

SMILES Cc1cc(Oc2cccc(F)c2F)ccc1-n1ncc(C(=O)c2nc3ccccc3[nH]2)c1N

InChI Key InChIKey=VLKGUDZPUCJLSH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352194   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352194({5-Amino-1-[4-(2,3-difluoro- phenoxy)-2-methyl-phe...)
Affinity DataIC50: 5nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Flouresence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent