BDBM352300 US9802939, I-70

SMILES COC(=O)Nc1ccc2c(c1)NC(=O)[C@@H](C(F)(F)F)/C=C/CC(NC(=O)/C=C/c1cc(Cl)ccc1-n1cnnn1)c1nc-2c(C)[nH]1

InChI Key InChIKey=PPEKXCCTMRZKQU-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352300   

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 352300BDBM352300(US9802939, I-70)
Affinity DataKi:  270nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent