BDBM352330 US9802939, I-265

SMILES COC(=O)Nc1ccc2c(c1)NC(=O)NCCC[C@H](NC(=O)/C=C/c1c(C(C)=O)ccc(Cl)c1F)c1nc-2c(C#N)[nH]1

InChI Key InChIKey=WVFUJAFIJVOLFJ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352330   

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 352330BDBM352330(US9802939, I-265)
Affinity DataKi:  133nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent