BDBM352371 US11098048, Example 2.28::US9802944, Example 2.28

SMILES O=C([C@@H]1CCc2[nH]nnc2C1)N1C[C@H]2CCN(CC[C@H]2C1)C(=O)c1cc(OCC2CCOCC2)cc(c1)C1CC1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 352371   

TargetAtaxin-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM352371(US11098048, Example 2.28 | US9802944, Example 2.28)
Affinity DataIC50:  7nMAssay Description:Assay working solutions were made as follows:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2), 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtaxin-2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM352371(US11098048, Example 2.28 | US9802944, Example 2.28)
Affinity DataIC50:  7nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent