BDBM352385 US9802944, Example 5.03

SMILES c1c(cc(nc1C2CC2)OCC3CCOCC3)C(=O)N4CC[C@@H]5CN(C[C@@H]5CC4)C(=O)N6CCc7c(onc7O)C6

InChI Key InChIKey=MFAFPFCSTKBXTH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352385   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352385(US9802944, Example 5.03)
Affinity DataIC50: 10nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent