BDBM352418 N ((S)-2-((3aS,6S,6aS)-6-chloro-3-oxotetrahydro-2H-furo[3,2-b]pyrrol-4(5H)-yl)-1-cyclopentyl-2-oxoethyl)-5-(5-fluoropyridin-3-yl)thiophene-2-carboxamide::US9802947, Compound Example 6

SMILES Fc1cncc(c1)-c1ccc(s1)C(=O)N[C@@H](C1CCCC1)C(=O)N1C[C@H](Cl)[C@H]2OCC(=O)[C@@H]12

InChI Key InChIKey=WZJDSWDMVYJVRT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 352418   

TargetCathepsin K(Human)
GrÜNenthal

US Patent
LigandPNGBDBM352418(US9802947, Compound Example 6 | N ((S)-2-((3aS,6S,...)
Affinity DataKi:  3.10nMAssay Description:Recombinant human cathepsins (CatS, CatK, CatL, CatB) were purchased from a Enzo Life Sciences. All assays were carried out in 96-well format using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

TargetCathepsin S(Human)
GrÜNenthal

US Patent
LigandPNGBDBM352418(US9802947, Compound Example 6 | N ((S)-2-((3aS,6S,...)
Affinity DataKi:  174nMAssay Description:Recombinant human cathepsins (CatS, CatK, CatL, CatB) were purchased from a Enzo Life Sciences. All assays were carried out in 96-well format using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent