BDBM352429 N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-c]pyridin-7-yl)-2-azabicyclo[2.2.1]heptan-7-yl)-2-chloro-4-(3-methyl-1H-1,2,4-triazol-1-yl)benzamide ::US9808445, 7.1::US9808445, 7.2

SMILES Cc1ncn(n1)-c1ccc(C(=O)N[C@@H]2[C@H]3CC[C@@H]2N(C3)c2ncc(Cl)c3c(N)noc23)c(Cl)c1

InChI Key InChIKey=KWAYYBDVPSPGPN-SDDDUWNISA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 352429   

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352429(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50:  550nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352429(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
PDB3D3D Structure (crystal)