BDBM352463 US9809545, 2Af

SMILES OC(=O)c1ccc(NC(=O)C(Cc2ccccc2)n2ccc(cc2=O)-c2cnccc2Cl)cc1

InChI Key InChIKey=UZYCGVGMTIMNJM-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352463   

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352463(US9809545, 2Af)
Affinity DataKi:  7.75E+3nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent