BDBM352466 US9809545, 3Bd

SMILES OC(=O)c1ccc2[nH]c(nc2c1)[C@H](Cc1ccc(F)cc1)n1ccc(cc1=O)-c1cc(Cl)ccc1-n1cnnn1

InChI Key InChIKey=IIUPZRYBYMOPHC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352466   

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352466(US9809545, 3Bd)
Affinity DataKi: <5nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
Go to US Patent